GS7340 impurity1

GS7340 impurity1 - Names and Identifiers

Name	phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Synonyms	GS7340 impurity1 GS7340 intermediate 1 Tenofovir Related Compound 2 phenyl ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate [[(1R)-2-(6-aMino-9H-purin-9-yl)-1-Methylethoxy]Methyl]-, Monophenylester phenylydrogen((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl) phosphonate phenyl hydrogen (R)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
CAS	379270-35-6
EINECS	807-851-4

GS7340 impurity1 - Physico-chemical Properties

Molecular Formula	C15H18N5O4P
Molar Mass	363.3083
Density	1.53±0.1 g/cm3(Predicted)
Melting Point	237-239°C
Boling Point	610.1±65.0 °C(Predicted)
Appearance	Form Solid, color White to Off-White
pKa	2.09±0.10(Predicted)
Storage Condition	Keep in dark place,Sealed in dry,Room Temperature
Use	It is an impurity of tenofovir alafenamine and is also used as an impurity control.

GS7340 impurity1 - Upstream Downstream Industry

Raw Materials

DIPHENYLIODIUM FLUORIDE
DIPHENYLIODONIUM HEXAFLUOROARSENATE
Tenofovir
DIPHENYLIODONIUM BROMIDE
DIPHENYL PHOSPHITE
DIPHENYLIODONIUM TRIFLUOROMETHANESULFONATE
Phenol
Triphenyl phosphite

GS7340 impurity1 - Introduction

[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy] methyl phosphate monophenyl ester is an organophosphate compound whose chemical structure contains a purine ring and is linked together with a phenyl group and a phosphate monoester group.

Nature:
-Appearance: White or light yellow solid
-Molecular formula: C17H21N5O4P
-Molecular weight: 407.36g/mol

Use:
[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy] methyl monophenyl phosphate is mainly used in the pharmaceutical field as a raw material or intermediate. It can be used in the synthesis of purine compounds in drug research, such as the development of antiviral drugs or anti-tumor drugs by modifying purine nucleotides.

Preparation Method:
[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy] methyl phosphate monophenyl ester is generally prepared by chemical synthetic methods. The specific synthetic steps may vary according to different literature reports and research needs.

Safety Information:
- [(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy] monophenyl methyl phosphate is a chemical and should be considered a drug.
-Please observe the safety procedures, wear appropriate protective gloves and glasses, avoid contact with skin and inhalation of dust. Keep good ventilation during operation.
-Keep away from fire and combustibles, and store in a cool, dry place.
-In the event of inhalation, skin contact or ingestion, seek medical advice immediately and carry information about the chemical.

Last Update：2024-04-09 19:05:53